GammaBind Plus Sepharose is a protein G affinity chromatography resin for purifying immunoglobulins (IgGs) from a variety of species.
- Enhanced binding to rat and mouse IgG subclasses compared with GammaBind G Sepharose.
- Binds to all mouse, rat, and human IgG subclasses; binds total IgG from guinea pig, rabbit, goat, cow, sheep, and horse.
- Lab-scale IgG purification yields up to 35mg human IgG/mL.
- Well suited for immunoprecipitation procedures.
Affinity chromatography resin for IgG purification
GammaBind Plus Sepharose is used to analyze and purify classes, subclasses, and fragments of immunoglobulins from any biological fluid or cell culture medium. This resin is also suitable for immunoprecipitation.
This affinity chromatography resin is GammaBind G, Type 3, covalently immobilized to Sepharose CL-6B by maleimide linkage. This recombinant form of streptococcal protein G binds strongly to the Fc region of IgG from a variety of mammalian species. In addition, many antibodies also interact via the Fab region with a low affinity site on Protein G.