A2169-25MG Display Image

3-Azido-3-deoxythymidine, >=98% (HPLC)

Code: A2169-25MG D2-231

Application

3′-Azido-3′-deoxythymidine has been used as the reverse transcriptase inhibitor to inhibit the viral genome integration and as an antimicrobial agent to evaluate ...


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€113.88 25MG
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Application

3′-Azido-3′-deoxythymidine has been used as the reverse transcriptase inhibitor to inhibit the viral genome integration and as an antimicrobial agent to evaluate its anti-Salmonella activity.

Biochem/physiol Actions

Azidothymidine (AZT), a thymidine analogue, is a reverse transcriptase inhibitor against the HIV-1 virus. Azidothymidine has been shown to decrease CRISPR-mediated homology-directed repair (HDR) efficiency.

Reverse transcriptase inhibitor active against HIV-1 virus.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

1 g in glass bottle

25 mg in glass insert

100, 250 mg in glass bottle

assay≥98% (HPLC)
formpowder
Gene Informationhuman ... HIVE1(3095)mouse ... Slc29a1(63959)
InChI keyHBOMLICNUCNMMY-XLPZGREQSA-N
InChI1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
mp113-115 °C (lit.)
Quality Level200
SMILES stringCC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
solubilityH2O: 50 mg/mL
storage temp.−20°C
Cas Number30516-87-1
This product has met the following criteria: