Amino Acid Sequence

Cer-Glc-Gal(NeuAc)-GalNAc

Biochem/physiol Actions

Minor component of cell membranes that has been shown to accumulate in Tay-Sachs disease.

General description

Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum. They contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. For classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.

Packaging

1 mg in serum bottle